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(S,R,S)-AHPC-PEG2-NH2 dihydrochloride

CAS No. 2341796-76-5

(S,R,S)-AHPC-PEG2-NH2 dihydrochloride( VH032-PEG2-NH2 dihydrochloride | VH032-linker 12 | VH032 amide-PEG2-amine )

Catalog No. M27014 CAS No. 2341796-76-5

(S,R,S)-AHPC-PEG2-NH2 dihydrochloride is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    (S,R,S)-AHPC-PEG2-NH2 dihydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    (S,R,S)-AHPC-PEG2-NH2 dihydrochloride is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker.
  • Description
    (S,R,S)-AHPC-PEG2-NH2 dihydrochloride is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker.(In Vitro):PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vitro
    PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vivo
    ——
  • Synonyms
    VH032-PEG2-NH2 dihydrochloride | VH032-linker 12 | VH032 amide-PEG2-amine
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2341796-76-5
  • Formula Weight
    648.64
  • Molecular Formula
    C28H43Cl2N5O6S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C([C@H]1N(C([C@@H](NC(COCCOCCN)=O)C(C)(C)C)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2.Cl.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Sagong HY, Kim KJ. Structural Insights into Substrate Specificity of Cystathionine γ-Synthase from Corynebacterium glutamicum. J Agric Food Chem. 2017 Jul 26;65(29):6002-6008.
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